Pedunculated atypical fibroxanthomas of the face
نویسندگان
چکیده
منابع مشابه
Copy number variations in atypical fibroxanthomas and pleomorphic dermal sarcomas
Atypical fibroxanthomas (AFX) and pleomorphic dermal sarcomas (PDS) are frequent cutaneous sarcomas typically arising on sun-exposed skin in elderly patients. In contrast to AFX, which generally do not recur after complete excision, PDS locally recur in up to 50% and metastasize in up to 20%. We recently detected characteristic UV-induced TP53 mutations as potential driver mutation in almost al...
متن کاملHyalin perivascular arcs and rings in sclerosing atypical fibroxanthomas.
Several variants of atypical fibroxanthoma (AFX) are split based on cytomorphology, for example, clear cell, granular cell, and spindle cell nonpleomorphic types. Nine cases of an unusual variant of AFX with keloidal tumoral sclerosis were presented by Kim and McNiff, following in from an anecdotal report and series of ‘‘keloidal’’ AFX. In several cases, ‘‘the keloidal collagen also formed ring...
متن کاملOncogene and therapeutic target analyses in atypical fibroxanthomas and pleomorphic dermal sarcomas
BACKGROUND Until now, almost nothing is known about the tumorigenesis of atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS). Our hypothesis is that AFX is the non-infiltrating precursor lesion of PDS. MATERIALS AND METHODS We performed the world-wide most comprehensive immunohistochemical and mutational analysis in well-defined AFX (n=5) and PDS (n=5). RESULTS In NGS-based mu...
متن کاملCD163 expression is present in cutaneous histiocytomas but not in atypical fibroxanthomas.
CD163, a hemoglobin scavenger receptor, is expressed in monocytes and macrophages. Recent work has shown that this marker is specific for neoplasms of histiocytic differentiation. Our aim was to test the ability of CD163 to separate cutaneous histiocytomas from their morphologic mimics. We tested the expression of CD163 in 78 cases, including 19 xanthogranulomas, 16 atypical fibroxanthomas, 6 r...
متن کاملFace-to-face interference in typical and atypical development
Visual communication cues facilitate interpersonal communication. It is important that we look at faces to retrieve and subsequently process such cues. It is also important that we sometimes look away from faces as they increase cognitive load that may interfere with online processing. Indeed, when typically developing individuals hold face gaze it interferes with task completion. In this novel...
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ژورنال
عنوان ژورنال: Dermatology Online Journal
سال: 2020
ISSN: 1087-2108
DOI: 10.5070/d32610050471